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Molecular Pathology & Targeted Treatments for Non-Small Cell Lung Cancer


Molecular Pathology & Targeted Treatments for Non-Small Cell Lung Cancer

When Nov 18, 2014 from 12:30 PM to 04:55 PM
Where Manchester
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This course provides a detailed description of the molecular pathology and classification of non-small cell lung cancer, along with information on targeted treatments in use and in development for this disease


Key Themes

Introduction to cancer: a disease of many layers

• DNA damage: causes, types and consequences

• Epigenetics – the chicken or the egg?

• Cancer cells and their microenvironment –

cellular diversity and cell-cell communication


• Cancer stem cells and the EMT

• Genetic instability and intra-tumoural

heterogeneity: the new enemies

Introducing non-small cell lung cancer

• Mechanisms of development

• The molecular landscape of adenocarcinoma and

squamous cell carcinoma

Targeted treatments for non-small cell lung cancer

• Matching mutations to drugs – strengths and


• EGF-R targeted treatments (gefitinib, erlotinib,

afatinib, dacomitinib & cetuximab)

• ALK inhibitors (crizotinib & LDK378)

• VEGF-R & multi-kinase inhibitors

• Immunotherapy (PD-1 and PDL-1 monoclonal



-       Delegate Fee: £60

-       Early Birds: £45 (before 18 Aug 2014)

-       Christie Staff: £30

-       NCRN Staff: £30

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