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Important clues to chemo resistance found

“Fish oils block chemotherapy drug,” BBC news has reported. The broadcaster said that tumours could become immune to treatment due to processes involving two fatty acids that are also produced by stem cells in the blood.

This news story is based on research carried out in the Netherlands that examined the role of a specific type of cell, called mesenchymal stem cells (MSCs), in the development of resistance to chemotherapy. Although these non-cancerous cells occur naturally in the body, some research has indicated that they can play a role in tumours growing and spreading. This latest research involved a series of experiments in mice to determine whether these cells were also involved in tumours developing drug resistance. It looked at whether they produced resistance against a variety of chemotherapy drugs.